Monday, September 28, 2020

XtalPi lands massive $319M SoftBank-led round C to continue its high-tech drug discovery

XtalPi, an American-Chinese biotech firm that focuses on AI-assisted drug discovery, has raised a $319 million round C from a slate of enthusiastic investors led by SoftBank’s Vision Fund. It joins numerous others with 9-figure rounds in what is clearly a valuable and competitive space.

XtalPi works with major pharmaceutical companies like Pfizer that need to identify promising new drug-like molecules and learn as much about them as possible. It’s very much a race, so companies claiming to use AI to speed up the process have attracted major funding. Though there have been no prominent breakthroughs to speak of resulting from the space, it’s hard to imagine any major player can afford to ignore it.

This company, founded in 2014, purports to offer extremely low-level simulation and prediction of target molecules, both simulating the physics at atomic levels and doing the more traditional data science work that eliminates dead ends and points towards more fruitful avenues for investigation.

Although these advances are in the digital space, the companies still need a large staff of skilled scientists who can verify and advance the results — as well as the facilities to support them. It may help speed up the slow-paced pharmaceutical industry, but that doesn’t mean it’s cheap or easy to do so.

AI-enhanced (which is really to say using machine learning techniques) biotech firms have attracted huge funding rounds and lucrative (or potentially lucrative) partnerships as pharma’s biggest companies place their bets. (Insitro founder Daphne Koller spoke on this topic just two weeks ago at Disrupt.)

XtalPi plans to use the money as you might expect: To scale its existing operations with improved algorithms, more data, and additional computing power.

“We believe AI holds the answer to solving pharma’s productivity challenge,” said chairman and co-founder Shuhao Wen in a press release. “More specifically, XtalPi’s AI-powered platform can improve the industry’s research efficiency and success rate in order to lower costs for discovering and developing new drugs. We look forward to applying our platform to help clients bring more first-in-class and breakthrough drugs to the market and address significant unmet medical needs to benefit patients on a global scale.”

Softbank led the round, with PICC Capital and Morningside making up the larger remaining part, as well as follow-ons from existing investors Tencent, Sequoia China, China Life, and SIG.

Indonesian fintech startup BukuWarung gets new funding to add financial services for small merchants

A month after completing Y Combinator’s accelerator program, BukuWarung, an financial tech startup that serves small businesses in Indonesia, announced it has raised new funding from a roster of high-profile investors, including partners of DST Global, Soma Capital and 20VC.

The amount of the funding was undisclosed, but a source told TechCrunch that it was between $10 million to $15 million. The new capital will be used to hire for BukuWarung’s technology team. TechCrunch first profiled BukuWarung in July.

Angel investors in the round include several high-profile founders and executives: finance technology platform Plaid’s co-founder William Hockey; Tinder co-founder Justin Mateen; Superhuman founder Rahul Vohra; Adobe chief product officer Scott Belsky; Clearbit chairman and startup advisor Josh Buckley; former Uber chief product officer Manik Gupta; Spotify’s former head of new markets in Asia Sriram Krishnan; 20VC founder Harry Stebbings; Nancy Xiao, an investor with Bond Capital; and Fast co-founder Allison Barr Allen. Angel investors from WhatsApp, Square and Airbnb also participated.

Launched last year by co-founders Chinmay Chauhan and Abhinay Peddisetty, BukuWarung is targeted at the 60 million “micromerchants” in Indonesia, including neighborhood store (or warung) owners. The app was originally created as a replacement for pen and apper ledgers, but plans to introduce financial services including credit, savings and insurance. In August, the company integrated digital payments into its platform, enabling merchants to take customer payments from bank accounts and digital wallets like OVO and DANA. BukuWarung’s goal is to fill the same role for Indonesian merchants that KhataBook and OKCredit do in India.

 

One of the reasons BukuWarung launched digital payments was in response to customer demand for contactless transactions and instant payouts during the COVID-19 pandemic. Since introducing the feature, the company said it has already processed several million U.S. dollars in total payment volume (TPV) on an annualized basis. The company says it now serves about 1.2 million merchants across 750 locations in Indonesia, focusing on tier 2 and tier 3 cities.

Digital payments is also the first step into building out BukuWarung’s financial services, which will help differentiate it from other bookkeeping. The payments features is currently free and BukuWarung is experimenting with different monetization models, including making a small margin on fees.

“The reason why we launched payments is also very strategic, because there is a lot of pull in the market. We have already seen several millions annualized TPV in less than a month, because the payments we offer are cost-efficient as well and cheaper than to get from a bank,” Chauhan told TechCrunch.

“If you look at the Indian players, like Khatabook, they have also launched digital payments. The reason for that is because it’s a very essential step for building a business and monetization,” he added. “If you don’t have payments, you can’t do anything like that.”

Chauhan added that building a financial services platform is the difference between providing a utility app that replaces bookkeeping ledgers, and becoming an essential service for merchants that will eventually include lending for working capital, savings and insurance products. The bookkeeping features on BukuWarung will feed into the financial services aspect by providing data to score creditworthiness, and help small merchants, who often have difficulty securing working capital from traditional banks, get access to lines of credit.

Microsoft outage leaves users unable to access Office, Outlook, Teams

Microsoft said it’s investigating an authentication outage with Office 365, preventing users from accessing some of the company’s most widely used services, including Office.com, Outlook.com, and Teams.

The company’s status dashboard said the issue started at 2:25pm PT, and has impacted mostly consumer users across the globe for the last few hours. Some government users may also be impacted, the company said.

In a series of tweets, Microsoft said that it tried to fix the issue, but was forced to roll back its changes after the fix failed.

For now, Microsoft said it was “rerouting traffic to alternate infrastructure to improve the user experience while we continue to investigate the issue.”

But that leaves millions on the U.S. west coast and users in Australia still unable to access their online services.

TechCrunch will keep you posted with developments. In the meantime, feel free to catch up with some of the bigger stories of the day.

Read more:

Boston- and Shenzhen-based XtalPi, which uses AI for drug discovery and development, raises $319M Series C led by SoftBank's Vision Fund (Devin Coldewey/TechCrunch)

Devin Coldewey / TechCrunch:
Boston- and Shenzhen-based XtalPi, which uses AI for drug discovery and development, raises $319M Series C led by SoftBank's Vision Fund  —  XtalPi, an American-Chinese biotech firm that focuses on AI-assisted drug discovery, has raised a $319 million round C from a slate of enthusiastic investors led by SoftBank's Vision Fund.



Microsoft is investigating an authentication error impacting multiple Microsoft 365 services, including Office, Teams, Power Platform, and Dynamic365 (Chris Duckett/ZDNet)

Chris Duckett / ZDNet:
Microsoft is investigating an authentication error impacting multiple Microsoft 365 services, including Office, Teams, Power Platform, and Dynamic365  —  Microsoft continuing to look into the problem after roll back fails to solve issue.  —  Microsoft is currently looking into an authentication error hitting its Office 365 systems.



Sunday, September 27, 2020

Karnataka High Court Answer Key 2020 – Civil Judge Prelims Provisional Key Released

Karnataka High Court has released answer key & objections for the post of Civil Judge (Prelims) (Advt No. CJR 01/2020).

Karnataka High Court 2020 – Civil Judge Prelims Provisional Key Released

Karnataka High Court has released answer key & objections for the post of Civil Judge (Prelims) (Advt No. CJR 01/2020).

BPSC 66 CCE Recruitment 2020 – Apply Online for 731 Vacancy

Bihar Public Service Commission (BPSC) recruits 731 66 CCE (Prelims) Exam 2020. Candidates with Any Degree can apply online from 28-09-2020 to 20-10-2020.

MSCWB Admit Card 2020 – Conservancy Mazdoor Interview Call Letter Download

West Bengal Municipal Service Commission has released Phase I interview admit card for the post of Conservancy Mazdoor (Advt No. 11 of 2020).

Samsung announces price cuts of up to Rs 1,000 for two phones

Samsung has cut prices of two M-series smartphones -- Galaxy M01 and Galaxy M11. The new prices of both the smartphones are reflecting on Samsung’s official website as well as on Amazon India website. https://ift.tt/3jegBgY

Realme Narzo 20A First Impressions

The Realme Narzo 20A starts at Rs. 8,499 in India and packs a Qualcomm Snapdragon 665 SoC along with a 5000mAh battery and triple camera setup. Is it all too good to be true? https://ift.tt/33ZgmA0

China Must Prepare for 'Long March' Amid US Restrictions on SMIC: State Media

China must engage in a new "long march" in the technology sector now that the US has imposed export restrictions on Semiconductor Manufacturing International Corp (SMIC), the country's largest chip... https://ift.tt/2GipRlr

Federal Judge Postpones Trump Ban on TikTok App Downloads

A federal judge on Sunday postponed a Trump administration order that would have banned the popular video sharing app TikTok from US smartphone app stores around midnight. https://ift.tt/3cNz1D3

Google Meet to Limit Meetings to 60 Minutes on Free Plans

Google's video chat platform Google Meet has announced that after September 30, free versions of Meet will be limited to meetings no longer than 60 minutes. https://ift.tt/2S1tq2c

Bharti Airtel vs Reliance Jio vs Vodafone: Biggest gainers and losers

https://ift.tt/3kQP7ym

Belgium-based Vertical Compute, a memory chip firm spun out of European VC firm Imec.xpand, raised a €20M seed led by Imec.xpand (Dean Takahashi/VentureBeat)

Dean Takahashi / VentureBeat : Belgium-based Vertical Compute, a memory chip firm spun out of European VC firm Imec.xpand, raised a €20M ...